Eef Hogervorst
Professor of Biological Psychology
Contact details
Room: U.2.14
Phone: +44 (0)1509 223020
Fax: +44 (0)1509 223940
Email: E.Hogervorst@lboro.ac.uk
Background
Eef Hogervorst did her PhD in at the University of Maastricht on the modelling of age-related cognitive decline. She subsequently worked at the Universities of Oxford (1998-2005), Arkansas Medical Sciences USA and Cambridge as a neuropsychologist and epidemiologist to investigate risk factors for Alzheimer's disease and age-related cognitive decline.
Research Interests
Early diagnoses and modifiable risk and protective factors (e.g. hormones, exercise and nutrition) for dementia and age-related cognitive decline; development and validation of cognitive tests and computerized diagnostic systems.
Current research
With the Universities of Oxford and Indonesia we have set up a large population study to investigate risk and protective factors for dementia and age-related cognitive decline which is funded by the Alzheimer's Research Trust. This will be linked to a cohort study of the ART Midlands group, involving clinics in Leicestershire, Birmingham and Sheffield (also see Applied Cognitive Research group).
Awards
- The Curt Richter Award of the International Society of Psychoneuroendocrinology, Trier, Germany (1998)
- The Blaschko fellowship (1998) and Somerville JR fellowship (1999-2003) at Oxford
- Recipient Junior faculty Poster Award Women’s Cognitive Health: the role of estrogen and other factors in dementia’ conference (November 8-10, 1999) in Winston-Salem, NC, U.S.A.
- For dementia diagnostics: the Leicester Best conference poster award Delivering the best Leicester Primary Care Alliance (14-7 2005)
Selected publications
- Hogervorst, E. The short-lived effect of HRT on cognition function (2006) Invited review. In: Rasgon NL (ed). The Effects of Estrogen on Brain Function. John Hopkins Press. Baltimore, MD.
- Hogervorst, E., Bandelow, S., Moffat, S.D. (2005). Increasing testosterone levels and effects on cognitive function in elderly men and wonen: a review. Current Drug Targets-CNS and Neurol Disorders, 4, 531-40
- Hogervorst, E. Bandelow, S., Combrinck, M. Irani, S.. & Smith, A.D. (2003b). The validity and reliability of 6 sets of clinical criteria to classify Alzheimer's disease and vascular dementia in post-mortem confirmed cases: added value of a decision- tree approach. Dementia;16(3):170-180
- Hogervorst, E., deJager, C., Budge, M., & Smith, A.D. (2004a). Serum levels of estradiol and testosterone and performance in different cognitive domains in healthy elderly men and women Psychoneuroendocrinology Volume 29, Issue 3, April 2004, Pages 405-421
- Hogervorst, E., Bandelow, S., Combrinck, M, Smith, A.D. (2004c). Low free testosterone is an independent risk factor in AD. Exp Gerontol. Nov-Dec;39(11-12):1633-9.
- Hogervorst, E., Williams, J.W., Budge, M., Riedel, W.J., Jolles, J. (2000c). The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: a meta-analyses. Neuroscience, 101 (3), 485-512.
You can view a fuller publications list on the University Publications Database.
External Activities
- Journal Activity
- Editor Faculty 1000 Women's Mental Reproductive Health
- Guest editorial staff duties: The Aging Male, Molecular and Cellular Endocrinology; BBA-Molecular Basis of Disease; Alzheimer Disease & Associated Disorders
- Journal Referee
- Reviewer for: Neuropsychopharmacology, Psychopharmacology, CNS Spectrums, Exp Opinion on Investigational Drugs, Exp Opinion Pharmacotherapy, Expert Opinion on Emerging Drugs; Expert Review of Neurotherapeutics; Current Pharmaceutical Design, Mechanisms of Ageing & Development, J of Alzheimer’s Disease, Alzheimer Disease & Associated Disorders, Perceptual and Motor Skills, Physiology & Behavior, Niological Psychology, Neuropsychologia, Applied Ergonomics, Eur J Clin Nutrition, Current Topics in Nutraceutical Research, Physiology & Behavior, Hormones & Behavior, Hormone Research, Clinical Breast Cancer, Human Reproduction Journals, Psychoneuroendocrinology, J Neuroendocrinology, Climacteric, Maturitas, Molecular and Cellular Endocrinology, The Aging Male, Age & Ageing, BBA-Molecular Basis of Disease, Archives of Internal Medicine (JAMA), Med J Austr , Clin Med Research, Biological Psychiatry, Archives of General Psychiatry, Br J Psychiatry, Neurology India, J of Neuroscience, Neurobiology of Aging, BMC Neurology, Neurology, JNNP, Annals of Neurology
- Learned Societies and Professional Affiliations
- 2005 Elected Young Fellow Royal Society of Medicine London
- 2007 Member Association for Psychological Science
- 2004- Scientific advisor British Andropause Society
- 2005- Member Women’s Health, U.S.A.
- 2006- Member International Society for the Study of the Aging Male (ISSAM)
- 2007 Member Alzheimer’s Research Trust East Midlands group
- 2002 Member Alzheimer’s Society, Member Alzheimer’s Research Trust
- 2006 Member British Society for Ageing Research
- Visiting Titles
- Honorary Visiting Senior Research Fellow University of Cambridge Department of Public Health and Primary Care
- Honorary Visiting Professor University of Respati, Department of Public health and Epidemiology, Yogyakarta and Jakarta, Java, Indonesia
- Invited Lecture / Keynotes
- 2005-2007 only:
- Hogervorst E, Bandelow S. Diagnosis of early dementia Acta Neuropsychiatrica Conference Buenos Aires Argentina Invited keynote speaker (50 min) Sept. 5-8 2007 (will also give separate talk on testosterone levels in dementia at this conference)
- Hogervorst, E. Testosterone and cognition in postmenopausal women. 18th meeting North American Menopause Society Invited keynote October 3-6 2007 Dallas Texas
- Hogervorst, E. Testosterone and well being in different cohorts. Invited paper as main speaker British Andropause Meeting RSM 28-30 March 2007 London
- Hogervorst E et al.. Dementia in Indonesia oral presentation at the International Dementia Conference Nairobi Africa, 10-13 April 2007
- Hogervorst, E. Androgens, genetic polymorphisms and Alzheimer;’s disease. Alzheimer’s association meeting Madrid July 16-21 2006 (invited key note speaker)
- Hogervorst, E. TSH and cognitive function in elderly of MRC CFAS. BSRA meeting St Anne’s college 12th of July 2006
- Hogervorst, E. Androgens and genetic variations in men with AD. Invited main speaker. The Aging Male 2006; 9 (1) March 2006 the World Conference on the Aging Male 2006 Feb 14-21, page 4.
- Hogervorst, E. Bandelow, S., Combrinck, M., Smith, A.D. Testosterone replacement may not be a good idea for everyone. Oral as main speaker and poster presentation Research Into Ageing/Help the Aged Grant holders conference Birmingham 5-6 September 2005
- Hogervorst, E. CAG polymorphisms and Alzheimer’s disease in men. Testosterone and Androgens Society. Royal Society, London, 23-26 February 2005 (invited lecture as main speaker)
- Advisory Roles
- from 2001 - Reviewer Alzheimer’s Association (U.S.A.) annual grant (NIRG, IIRG, Zenith) applications
- 2007 Member of the European Scientific Referee panel for the European Research Area in Ageing (ERA-AGE) project (the Future Leaders of Ageing Research, FLARE) funding programme
- 2006-2010 Member Medical Research Council College of Experts (reviewing grant applications, advisory function on new schemes and strategic review, participate in Special Review Panels etc)
- 2006 Reviewer for SPARC grant applications– Awards for Ageing Research (EPSRC/BBSRC)
- 2006 Reviewer Netherlands Organisation for Scientific Research (NWO) grants for ‘Veni program’
- Collaborative Research
- We have collaborations with the following research groups: MRC CFAS (University of Cambridge) OPTIMA (University of Oxford) and RAMS, H-ABC, WHIMS and KEEPS in the USA. These are multi-centre studies involving the Universities of Stanford, Wisconsin Maddison, UCLA, UCSF, Harvard, Yale etc.
- Commercialisation of Research
- The Applied Cognitive Research group regularly does consultancies for pharmaceutical industry
- Other Evidence of Esteem
- Scientific Organizer, Initiator and Head of Scientific Organising Committee of the Expert meeting/conference ‘Hormones, cognition and dementia’ in Loughborough U.K. 18-21 March